In the past two decades, the incidence of rubella infection has decreased due to a nation-wide rubella vaccination program. Therefore the rate of rubella Ig G antibody has decreased. This means an increasing vulnerability to rubella infection
among
the
group, with negative Ig G antibodies.
The study was conducted in January of 1996. The subjects were 1,010 fertile women(ages 20¡45 years). The study was performed at Park Women's Clinic to investigate the status of rubella antibody in Korean fertile women.
@ES The results were as follows.
@EN 1. The positive rate of rubella Ig G and Ig M antibody were 80.5% and 1.5%. respectively.
2. The mean age of positive rubella Ig G group was 28.5¡¾3.6 years. The positive rate of rubella Ig G antibody was decreased by an increase in age with a significant level at p<0.05.
3. The positive rate of rubella IgG antibody was 63.3% in 1992, 71.3% in 1993, 87.5% in 1994, 81.1% in 1993, 87.5% in 1994, 91.1% in 1995 and 83.8% in 1996. The increase in the positive rate of rubella Ig G antibody by year for 5 years was
statisticalliy significant at p<0.05.
4. The positive rubella Ig M antibody was noted in 15 women. Among them, one woman was tested in 1993, 5 women in 1995 and 9 women in 1996. The incidence of rubella infection had increased by years, and was statistically significant at p<0.05.
5. The mean titer of rubella Ig G antibody was 47.18¡¾50.04 Iu/ml. The titer of rubella Ig G antibody was decreased by the increase in at age(p<0.05).
We observed a low positive rate of rubella Ig G antibody as compaired with other studies that were performed before 1990. Therefore, to prevent sporadic rubella infections, rubella vaccinations should be given to unmarried women.
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